Link between asthma symptoms and air pollution is modified by genetic differences

Asthma is a complex disorder that is made up of both heritable genetic factors and environmental exposures. There are a number of genetic mutations that change a single letter in the DNA of a gene, called single nucleotide polymorphisms or SNPs, which have been linked risk for asthma. Many of these SNPs are in genes…

In Bradford UK, 1 in every 3 new cases of asthma may be attributable to air pollution

Air pollution, specifically that originating from diesel engines, has been linked with increased risk of developing asthma, worsening of asthma symptoms, and increased risk of hospitalization due to asthma related problems. Nitrogen oxides (NO2, NOx) and small particulate matter, produced by the combustion of diesel, are considered to be the offending compounds that are linked to asthma…

Predicting asthma risk at 1 year of age

Asthma is a disease that makes breathing difficult for 2.4 million Canadians. It is caused by excessive inflammation and abnormally thick airway walls. There are numerous known risk factors for asthma including genetics but much is still unknown about the development of the disease. Asthma is part of the atopic march, a phenomenon that often…

Exposure to pollution in utero increase the risk of lung inflammation in mice for 3 generations

New research published monthly continues to shed light on the negative health effects of air pollution which include aggravation of existing cardiovascular and respiratory diseases, development of chronic diseases like asthma and heart disease, and even an early risk of death. Traditionally considered to be reserved for severe pollution events, the health concerns surrounding air…

One third of adults with asthma may be misdiagnosed

You go to your family doctor complaining of difficulty breathing, wheezing, tightness in your chest, and a cough. Your doctor listens to your chest, makes some notes and diagnoses you with asthma. You get some inhalers to control the symptoms and carry on your way. Surprisingly, there was never a test done to determine if…